Biopharmaceutics MCQs | Part-3

Biopharmaceutics MCQs (Part-3)

This free quiz test on biopharmaceutics will help you to prepare for competitive exams or interviews.

1 / 25

In the sequence of events in drug absorption from orally administered tablet, which one
comes at first:

Disintegration

Deaggregation

Dissolution

Absorption

2 / 25

Absorption mechanism through rectal route is:

Endocytosis

Facilitated diffusion

Passive diffusion

Pore transport

3 / 25

Clearance is:

Hypothetical volume of body fluids containing drug from which the drug is completely removed in specified period of time.

Time period in which drug is completely removed from body.

Amount of drug that is completely removed from body in specified period of time.

Fraction of drug that is completely removed from body in specified period of time.

4 / 25

Oral bioavailability of a drug depends upon:

Half life of drug

Rate of elimination

Rheology of GI fluid

Extent of absorption & first pass effect

5 / 25

What is the correct order of bioavailability of different dosage forms?

Solutions > Emulsion > Capsules > Tablet > SR Tablet

Solutions > Emulsion > Tablet > Capsules > SR Tablet

Emulsion > Solutions > Tablet > Capsules > SR Tablet

Emulsion > Solutions > Capsules > Tablet > SR Tablet

6 / 25

The cell membrane is:

Semipermeable

Impermeable

Permeable

Permeable only to gases

7 / 25

The movement of drug between one compartment and other like blood or extravascular
tissue is referred to as:

Drug Disposition

Drug Distribution

Drug Binding

Drug Elimination

8 / 25

Which of the following has very high perfusion rate?

Fat and bone

Muscle and skin

Liver and heart

None of them

9 / 25

Which of the following has very low perfusion rate?

Fat and bone

Muscle and skin

Lungs and kidneys

Liver and heart

10 / 25

Which is the primary site for metabolism?

Liver

Kidneys

Lungs

Intestines

11 / 25

Which of the following is correct decreasing order of drug metabolism?

Liver》lungs》kidneys 》placenta》adrenals》intestines 》skin

Liver》lungs》kidneys 》intestines 》placenta》adrenals》skin

Kidneys 》intestines 》liver 》lungs》placenta

Kidneys 》intestines 》lungs 》liver 》skin

12 / 25

Which of the following processes proceeds in second phase of biotransformation?

Reduction

Acetylation

Hydrolysis

Oxidation

13 / 25

First pass metabolism occurs in:

Liver

Kidneys

Pancreas

Intestines

14 / 25

Which one of the following is principal organ for drug excretion:

Lungs

Liver

Kidneys

Sweat glands

15 / 25

Which compound are excreted through lungs:

Lipophilic

Gaseous

Liquid and hydrophilic

Solids less than 100 dalton’s

16 / 25

What is the mechanism of drug excretion for skin excretion:

Active secretion

Glomerular secretion

Passive diffusion

Passive reabsorption

17 / 25

What is driving force of glomerular filtration:

Concentration gradient

Hydrostatic pressure of plasma

High amount of aqueous pores

Hydrostatic pressure of blood flow

18 / 25

Which of the following is not factor influencing pulmonary excretion:

Pulmonary blood flow

The solubility of volatile substances

Rate of respiration

Heart rate

19 / 25

How do you calculate the rate of excretion by kidneys:

Rate of filtration- rate of secretion- rate of absorption

Rate of filtration + rate of secretion – rate of absorption

Rate of filtration + rate of secretion + rate of absorption

Rate of filtration – rate of secretion + rate of absorption

20 / 25

What is mean by IVIVC:

In Vitro In Vivo correlation

In vivo In vivo correlation

In vitro In vitro correlation

21 / 25

High solubility and High permeability is BCS class:

Class I

Class II

Class III

Class IV

22 / 25

Low solubility and High permeability is BCS class:

Class I

Class II

Class III

Class IV

23 / 25

High solubility and Low permeability is BCS class:

Class I

Class II

Class III

Class IV

24 / 25

Low solubility & Low permeability is BCS class:

Class I

Class II

Class III

Class IV

25 / 25

Drugs that activate receptors to accelerate or slow normal cellular function:

Antagonist

Agonists

Disposition

Lipoidal

Your score is

The average score is 62%

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