What is the Role of Antifoaming Agents in Dissolution Testing?
The dissolution medium contains a surfactant, like sodium lauryl sulfate (SLS) or Tween 80. The test begins smoothly, but soon enough, foam starts building up—slowly at first, then rising relentlessly. Before you know it, there’s foam all over the place, making sampling impossible and throwing your entire test off balance. Frustrating, right? The “Eureka” Moment!…
